Tags: Drug.
Muromonab-CD3 (trade name Orthoclone OKT3 marketed by Janssen-Cilag) is an immunosuppressant drug given to reduce acute rejection in patients with organ transplants. It is a monoclonal antibody targeted at the CD3 receptor a membrane protein on the surface of T cells. It was the first monoclonal antibody to be approved for clinical use in humans.