Tags: Protein.

Mothers against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SAMD5 gene.SMAD5 as its name describes is a homolog of the Drosophila gene: Mothers against decapentaplegic. It belongs to the SMAD family of proteins which belong to the TGFβ superfamily of modulators. Like many other TGFβ family members SMAD5 is involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP’s).

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