Tags: Drug.
Mizoribine (INN trade name Bredinin) is an immunosuppressive drug. The compound was first observed in Tokyo Japan in 1971. It is a natural product first isolated from the mould Eupenicillium brefeldianum. Mizoribine (MZB) is an imidazole nucleoside that has been used in renal transplantation and in steroid-resistant nephrotic syndrome IgA nephropathy lupus as well as for adults with rheumatoid arthritis lupus nephritis and other rheumatic diseases.