Tags: Protein.
Microcephalin (MCPH1) is a gene that is expressed during fetal brain development. Certain mutations in MCPH1 when homozygous cause primary microcephaly — a severely diminished brain. Hence it has been assumed that variants have a role in brain development but in normal individuals no effect on mental ability or behavior has yet been demonstrated in either this or another similarly studied microcephaly gene ASPM.
