Tags: Chemical Compound, Chemical Substance.

Michellamine is an atropisomeric alkaloid which has been found to be a strong anti-HIV viral replication inhibitor. It was discovered in the leaves of the Ancistrocladus korupensis which is a member of the Triphyophyllum peltatum found in Cameroon. There are 3 michellamines represented as A B and C however Michellamine B is the most active against the NID-DZ strain of HIV-2.

Michellamine.png
IUPAC name
(1R3R1’R3’R)-55’-(11’-dihydroxy-88’-dimethoxy-66’-dimethyl-22’-binaphthalene-44’-diyl)bis(13-dimethyl-1234-tetrahydroisoquinoline-68-diol)

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