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Methylone also known as M1 34-methylenedioxy-N-methylcathinone MDMC or bk-MDMA is an entactogen and stimulant of the phenethylamine amphetamine and cathinone classes. It was first synthesized by chemists Peyton Jacob III and Alexander Shulgin in 1996 for potential use as an antidepressant. Methylone is a close structural analogue of MDMA differing by the addition of a β-ketone group.

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