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Methylisopropyllysergamide (lysergic acid methylisopropyl amide MIPLA) is an analogue of LSD that was originally discovered by Albert Hofmann at Sandoz during the original structure-activity research into LSD. It has subsequently been investigated in more detail by the team led by David E. Nichols at Purdue University. Methylisopropyllysergamide is a structural isomer of LSD with the alkyl groups on the amide nitrogen having been subjected to a methylene shuffle.

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