Tags: Chemical Compound, Chemical Substance.

Metanephrine (metadrenaline) is a metabolite of epinephrine (adrenaline) created by action of catechol-O-methyl transferase on epinephrine. An article in the Journal of the American Medical Association 2002 indicated that the measurement of plasma free metanephrines is the best tool in the diagnosis of pheochromocytoma an adrenal medullary neoplasm.

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