Tags: Disease.
Melnick–Needles syndrome (MNS) also known as Melnick–Needles osteodysplasty is an extremely rare congenital disorder that affects primarily bone development. Patients with Melnick–Needles syndrome have typical faces (exophthalmos full cheeks micrognathia and malalignment of teeth) flaring of the metaphyses of long bones s-like curvature of bones of legs irregular constrictions in the ribs and sclerosis of base of skull.In males the disorder is nearly always lethal in infancy.