Tags: Protein.
NAD-dependent malic enzyme mitochondrial is a protein that in humans is encoded by the ME2 gene.This gene encodes a mitochondrial NAD-dependent malic enzyme a homotetrameric protein that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene.