Tags: Protein.
Mediator of DNA damage checkpoint protein 1 is a protein that in humans is encoded by the MDC1 gene.The protein encoded by this gene contains an N-terminal forkhead domain two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage.