Tags: Chemical Compound, Chemical Substance.

Mazapertine (RWJ-37796) is an antipsychotic agent that was developed by Johnson & Johnson but never marketed. It exerts its pharmacological effect through affinity for dopamine D2 serotonin 5-HT1A and α1-adrenergic receptors.Mazapertine is safe and well tolerated when administered orally.Analogs of mazapertine with conformational restriction have been prepared and have greater affinity for the 5-HT1A receptor.

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