Tags: Protein.
The MATH domain in molecular biology is a binding domain that was defined originally by a region of homology between otherwise functionally unrelated domains the intracellular TRAF-C domains of TRAF proteins and a C-terminal region of extracellular meprins A and B.Although apparently functionally unrelated intracellular TRAFs and extracellular meprins share a conserved region of about 180 residues the meprin and TRAF homology (MATH) domain.