Tags: Protein.
Mitogen-activated protein kinase kinase kinase 1 is an enzyme that in humans is encoded by the MAP3K1 gene.MAP3K or MEK kinase is a serine/threonine kinase that occupies a pivotal role in a network of phosphorylating enzymes integrating cellular responses to a number of mitogenic and metabolic stimuli including insulin (MIM 176730) and many growth factors.[supplied by OMIM]Mouse genetics has revealed that the kinase is important in: correct embryogenesis keratinocyte migration T cell cytokine production and B cell antibody production.