Tags: Protein.
Microtubule-actin cross-linking factor 1 isoforms 1/2/3/5 is a mammalian protein encoded by the MACF1 gene. MACF1 belongs to a subset of +TIPs or proteins which bind to growing microtubule ends called spectraplakins. Spectraplakins characteristically have distinctive microtubule and actin binding domains which allow MACF1 to bind to both cytoskeletal elements. MACF1 goes by many names and is also called ACF7 or actin cross-linking factor 7 MACF macrophin trabeculin α and ABP620.