Tags: Drug.
Luzindole (N-0774) (N-acetyl-2-benzyltryptamine) is a drug used in scientific research to study the role of melatonin in the body. Luzindole acts as a selective melatonin receptor antagonist with approximately 11- to 25-fold greater affinity for the MT2 over the MT1 receptor. In animal studies it has been observed to disrupt the circadian rhythm as well as produce antidepressant effects.