Tags: Enzyme.

In enzymology lovastatin nonaketide synthase (EC 2.3.1.161) is an enzyme that catalyzes the chemical reactionacetyl-CoA + 8 malonyl-CoA + 11 NADPH + 10 H+ + S-adenosyl-L-methionine dihydromonacolin L + 9 CoA + 8 CO2 + 11 NADP+ + S-adenosyl-L-homocysteine + 6 H2OThe 5 substrates of this enzyme are acetyl-CoA malonyl-CoA NADPH H+ and S-adenosyl-L-methionine whereas its 6 products are dihydromonacolin L CoA CO2 NADP+ S-adenosyl-L-homocysteine and H2O.This enzyme belongs to the family of transferases specifically those acyltransferases transferring groups other than aminoacyl groups.

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