Tags: Drug.
Loperamide/simethicone is combination medication marketed under the trade name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC Inc.Loperamide is a μ-opioid receptor agonist that works in the intestines. Although it is an opioid it has no effects on the central nervous system.