Lomustine (or CCNU; marketed under the name CeeNU in U.S.) is an alkylating nitrosourea compound used in chemotherapy. It is in the same family as streptozotocin. This is a highly lipid soluble drug and thus crosses the blood-brain barrier. This property makes it ideal for treating brain tumors and is its primary use. Lomustine has a long time to nadir (the time when white blood cells reach their lowest number).
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