Tags: Drug.

Lisofylline (LSF) is a synthetic small molecule with novel anti-inflammatory properties. LSF can effectively prevent type 1 diabetes in preclinical models and improves the function and viability of isolated or transplanted pancreatic islets. It is a metabolite of pentoxifylline.As well LSF improves cellular mitochondrial function and blocks interleukin-12 (IL-12) signaling and STAT-4 activation in target cells and tissues.

Lisofylline.svg
CAS number
100324-81-0
FDA UNII code
L1F2Q2X956
IUPAC name
1-[(5R)-5-Hydroxyhexyl]-37-dimethyl-37-dihydro-1H-purine-26-dione
PubChem
501254

Loading...

This page contains content from the copyrighted Wikipedia article "Lisofylline"; that content is used under the GNU Free Documentation License (GFDL). You may redistribute it, verbatim or modified, providing that you comply with the terms of the GFDL.