Tags: Drug.

Linaclotide (marketed under the trade name Linzess and Constella) is an peptide agonist of guanylate cyclase 2C that is undergoing clinical trials for use in treating abdominal pain in patients with irritable bowel syndrome (IBS) accompanied by constipation. The drug also has promising outlooks for the treatment of gastroparesis ulcerative colitis chronic intestinal pseudo-obstruction (CIPO) and inertia coli as well.

Linaclotide_structure.svg
ATC prefix
A06
ATC suffix
AX04
CAS number
851199-59-2
FDA UNII code
N0TXR0XR5X
IUPAC name
(L)-Cysteinyl-(L)-cysteinyl-(L)-glutamyl-(L)-tyrosyl-(L)-cysteinyl-(L)-cysteinyl-(L)-asparaginyl-(L)-prolyl-(L)-alanyl-(L)-cysteinyl-(L)-threonylglycyl-(L)-cysteinyl-(L)-tyrosine cyclo(1-6)(2-10)(5-13)-tris(disulfide)
PubChem
16158208

Loading...

This page contains content from the copyrighted Wikipedia article "Linaclotide"; that content is used under the GNU Free Documentation License (GFDL). You may redistribute it, verbatim or modified, providing that you comply with the terms of the GFDL.