Tags: Disease.

Leydig cell hypoplasia (or aplasia) (LCH) also known as Leydig cell agenesis is a rare autosomal recessive genetic and endocrine syndrome affecting an estimated 1 in 1000000 biological males. It is characterized by an inability of the body to respond to luteinizing hormone (LH) a gonadotropin which is normally responsible for signaling Leydig cells of the testicles to produce testosterone and other androgen sex hormones.

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