Tags: Enzyme.
In enzymology a leukotriene-E4 20-monooxygenase (EC 1.14.13.34) is an enzyme that catalyzes the chemical reaction(7E9E11Z14Z)-(5S6R)-6-(cystein-S-yl)-5-hydroxyicosa-791114- tetraenoate + NADPH + H+ + O2 20-hydroxyleukotriene E4 + NADP+ + H2OThe 5 substrates of this enzyme are (7E9E11Z14Z)-(5S6R)-6-(cystein-S-yl)-5-hydroxyicosa-791114- tetraenoate NADPH H+ and O2 whereas its 3 products are 20-hydroxyleukotriene E4 NADP+ and H2O.This enzyme belongs to the family of oxidoreductases specifically those acting on paired donors with O2 as oxidant and incorporation or reduction of oxygen.