Tags: Enzyme.
In enzymology a lactoylglutathione lyase (EC 4.4.1.5) (also known as glyoxalase I) is an enzyme that catalyzes the isomerization of hemithioacetal adducts which are formed in a spontaneous reaction between a glutathionyl group and aldehydes such as methylglyoxal.glutathione + methylglyoxal hemithioacetal adduct (R)-S-lactoylglutathioneGlyoxalase I derives its name from its catalysis of the first step in the glyoxalase system a critical two-step detoxification system for methylglyoxal.
