Tags: Chemical Compound, Chemical Substance.

Kyotorphin (L-tyrosyl-L-arginine) is a neuroactive dipeptide which plays a role in pain regulation in the brain. It was first isolated from bovine brain by Japanese scientists in 1979. Kyotorphin was named for the site of its discovery Kyoto Japan and because of its morphine- (or endorphin-) like analgesic activity. Kyotorphin has an analgesic effect but it does not interact with the opioid receptors. Instead it acts by releasing met-enkephalin and stabilizing it from degradation.

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