Tags: Protein.
Kringle Domains are autonomous protein domains that fold into large loops stabilized by 3 disulfide linkages. These are important in protein-protein interactions with blood coagulation factors. The name Kringle comes from the Scandinavian pastry that these structures resemble.Kringle domains have been found in plasminogen hepatocyte growth factors prothrombin and apolipoprotein(a).Kringles are found throughout the blood clotting and fibrinolytic proteins.
