Tags: Protein.
Ly-49 receptors or killer cell lectin-like receptor subfamily A (KLRA) are a class of natural killer cell receptor. Ly-49 proteins are a diverse set of C-type lectins that are expressed on NK cells in some mammals including rodents but not humans. Their primary function is to bind host MHC class I as a mechanism of self/health recognition. Upon binding ligands most Ly-49 receptors will deliver an inhibitory signal preventing killing of the target cell.