Tags: Disease.
Dominant optic atrophy or dominant optic atrophy Kjer’s type is an autosomally inherited disease that affects the optic nerves causing reduced visual acuity and blindness beginning in childhood. This condition is due to mitochondrial dysfunction mediating the death of optic nerve fibers. Dominant optic atrophy was first described clinically by Batten in 1896 and named Kjer’s optic neuropathy in 1959 after Danish ophthalmologist Poul Kjer who studied 19 families with the disease.