Tags: Protein.
Importin subunit alpha-1 is a protein that in humans is encoded by the KPNA1 gene.Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair.