Tags: Chemical Compound, Chemical Substance.

K252a is an alkaloid isolated from Nocardiopisis sp. soil fungi. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1.8 and 1.7 nmol/L respectively).

(+)-K252a.svg
IUPAC name
(9S-(9α10β12α))-239101112-hexahydro-10-hydroxy-10-(methoxycarbonyl)-9-methyl-912-epoxy-1H-diindolo[123-fg:3'2'1'-kl]pyrrolo[34-i][16]benzodiazocin-1-one

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