Tags: Drug.
JWH-198 is a drug from the aminoalkylindole family which acts as a cannabinoid receptor agonist. It was invented by the pharmaceutical company Sanofi-Winthrop in the early 1990s. JWH-198 has a binding affinity at the CB1 receptor of 10nM binding around four times more tightly than the parent compound JWH-200 which has no substitution on the naphthoyl ring. It has been used mainly in molecular modelling of the cannabinoid receptors.