Tags: Chemical Compound, Chemical Substance.
Joro spider toxin (joro toxin JSTX) – a toxin which was originally extracted from the spider Nephila clavata venom. The compound has demonstrated the ability to selectively block postsynaptic glutamate potentials AMPA glutamate receptors and to antagonise the effect of NMDA receptors in the CNS of vertebrates. However it does not affect aspartate-induced neural depolarization resting membrane potential nerve terminal spontaneous signalling or inhibitory postsynaptic potentials.
