Tags: Disease.

Janeway lesions are non-tender small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are indicative of infective endocarditis. Pathologically the lesion is described to be a microabscess of the dermis with marked necrosis and inflammatory infiltrate not involving the epidermis. They are caused by septic emboli which deposit bacteria forming microabscesses.

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