Tags: Drug.

Ispronicline (TC-1734 AZD-3480) is a drug which acts as a partial agonist at neural nicotinic acetylcholine receptors. It is subtype-selective binding primarily to the α4β2 subtype. It has antidepressant nootropic and neuroprotective effects and is under development for the treatment of dementia and Alzheimer’s disease. Clinical trials so far have shown ispronicline to be effective and well tolerated with the main side effects being dizziness and headache.

Ispronicline.png
ATC prefix
none
CAS number
252870-53-4
FDA UNII code
3E05NBH9V5
IUPAC name
(2S4E)-5-(5-isopropoxypyridin-3-yl)-N-methylpent-4-en-2-amine
PubChem
9824145

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