Tags: Chemical Compound, Chemical Substance.
Isopropylmalic acid (isopropylmalate) is an intermediate in the biosynthesis of leucine synthesized from oxoisovalerate by 2-isopropylmalate synthase and converted into isopropyl-3-oxosuccinate by 3-isopropylmalate dehydrogenase. Two isomers are important the 2- and 3-isopropyl derivatives and these are interconverted by isopropylmalate dehydratase.