Isaac Komnenos or Comnenus (Greek: Ἰσαάκιος Κομνηνός Isaakios Komnēnos; 16 January 1093 – after 1152) was the third son of Byzantine Emperor Alexios I Komnenos (r. 1081–1118) and Empress Irene Doukaina. He was raised to the high rank of sebastokrator by his older brother John II Komnenos but they later fell out and Isaac was exiled by John for several years.