Tags: Drug.

Irinotecan (Camptosar Pfizer; Campto Yakult Honsha) is a drug used for the treatment of cancer.Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. In chemical terms it is a semisynthetic analogue of the natural alkaloid camptothecin.Its main use is in colon cancer in particular in combination with other chemotherapy agents.

Irinotecan.svg
ATC prefix
L01
ATC suffix
XX19
CAS number
100286-90-6
DrugBank
DB00762
FDA UNII code
7673326042
IUPAC name
(S)-411-diethyl-341214-tetrahydro-4-hydroxy-, 9-yl-[14’bipiperidine]-1’-carboxylate, 314-dioxo1H-pyrano[3’4’:67]-indolizino[12-b]quinolin-
PubChem
60838

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