Tags: Protein.
Transmembrane ion channel family was defined in InterPro and Pfam as the family of tetrameric sodium potassium and calcium ion channels in which two C-terminal transmembrane helices flank a loop which determines ion selectivity of the channel pore. This large group of ion channels apparently includes families 1.A.1 1.A.2 1.A.3 and 1.A.4 of transporter classification.
