Tags: Drug.
Iodine (125I) CC49 is an iodine-125 radiolabelled monoclonal antibody for the detection of tumours. It is used in radioimmunoassays such as CA 72-4.CC49 has also been tested for the treatment of solid tumours but without success. Iodine (131I) CC49 and lutetium (177Lu) CC49 for example were shown to induce human anti-mouse antibodies; no tumour response was observed in Phase I and II clinical trials.