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Iodine-123 (123I or I-123) is a radioactive isotope of iodine used in nuclear medicine imaging including single photon emission computed tomography (SPECT). The isotope’s half-life is 13.22 hours; the decay by electron capture to tellurium-123 emits gamma radiation with a predominant energy of 159 keV (this is the gamma primarily used for imaging). In medical applications the radiation is detected by a gamma camera. The isotope is typically applied as iodide-123 the anionic form.