The interleukin-18 receptor (IL-18R) is an interleukin receptor of the immunoglobulin superfamily. IL-18R is a heteromeric complex of alpha- and beta-chains encoded by the genes IL18R1 and IL18RAP respectively.Endometrial IL-18 receptor mRNA and the ratio of IL-18 binding protein to interleukin 18 are significantly increased in adenomyosis patients in comparison to normal people indicating a role in its pathogenesis.
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