Tags: Protein.
In molecular biology intercellular adhesion molecules (ICAMs) and vascular cell adhesion molecule-1 (VCAM-1) are part of the immunoglobulin superfamily. They are important in inflammation immune responses and in intracellular signalling events. The ICAM family consists of five members designated ICAM-1 to ICAM-5. They are known to bind to leucocyte integrins CD11/CD18 such as LFA-1 and Macrophage-1 antigen during inflammation and in immune responses.