Tags: Disease.
An imperforate anus or anorectal malformations (ARMs) are birth defects in which the rectum is malformed. ARMs are a spectrum of different congenital anomalies in males and females that varies from fairly minor lesions as well as complex anomalies. The cause of ARMs is unknown the genetic basis of these anomalies is very complex because of their anatomical variability in an 8% of patients genetic factors are clearly associated with ARMs.
