Tags: Drug.

Idelalisib (codenamed GS-1101 or CAL-101) is a drug under investigation for the treatment of chronic lymphocytic leukaemia. It is in Phase III clinical trials testing drug combinations with rituximab and/or bendamustine as of 2013. The substance acts as a phosphoinositide 3-kinase inhibitor; more specifically it blocks P110δ the delta isoform of the enzyme phosphoinositide 3-kinase.

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