Tags: Drug.
IC-26 (WIN 1161-3 Methiodone) is an analogue of the opioid analgesic methadone where the carbonyl group has been replaced by the bioisosteric sulfone group. Human and animal studies suggest that IC-26 is around the same potency as methadone although other studies have found its activity to be inconsistent between different patients with consistent opioid activity only being seen at a dose several times that of methadone.
