Tags: Drug.
Ibrutinib (USAN also known as PCI-32765 and marketed in the U.S. under the name Imbruvica) is an anticancer drug targeting B-cell malignancies. It was approved by the US FDA in November 2013 for the treatment of mantle cell lymphoma and in February 2014 for the treatment of chronic lymphocytic leukemia. It is an orally-administered selective and covalent inhibitor of the enzyme Bruton’s tyrosine kinase (BTK).