Tags: Chemical Compound, Chemical Substance.
IBMX 3-isobutyl-1-methylxanthine like other methylated xanthine derivatives is both a competitive nonselective phosphodiesterase inhibitor which raises intracellular cAMP activates PKA inhibits TNF-alpha and leukotriene synthesis and reduces inflammation and innate immunity and nonselective adenosine receptor antagonist.As a phosphodiesterase inhibitor IBMX has IC50 = 2-50 μM and does not inhibit PDE8 or PDE9.
