Tags: Enzyme.
In enzymology a hydroxymethylglutaryl-CoA hydrolase (EC 3.1.2.5) is an enzyme that catalyzes the chemical reaction(S)-3-hydroxy-3-methylglutaryl-CoA + H2O CoA + 3-hydroxy-3-methylglutarateThus the two substrates of this enzyme are (S)-3-hydroxy-3-methylglutaryl-CoA and H2O whereas its two products are CoA and 3-hydroxy-3-methylglutarate.This enzyme belongs to the family of hydrolases specifically those acting on thioester bonds.