Tags: Protein.
Testosterone 17-beta-dehydrogenase 3 is an enzyme that in humans is encoded by the HSD17B3 gene.This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.