Tags: Enzyme.
Homogentisate 12-dioxygenase (homogentisic acid oxidase homogentisicase) is an enzyme which catalyzes the conversion of homogentisate to 4-maleylacetoacetate. Homogentisate 12-dioxygenase or HGD is involved in the catabolism of aromatic rings more specifically in the breakdown of the amino acids tyrosine and phenylalanine. HGD appears in the metabolic pathway of tyrosine and phenylalanine degradation once the molecule homogentisate is produced.
